Umm ... I think I'm going to restrict her to mostly anime and manga series stuff, so she won't recognize CSI at all. Avatar, I'd have to do some checking on. If it was dubbed in Japanese and aired in Japan at some point, there's a small chance of it?

Vocaloid, the chance is HUGE that she'd recognize, seeing how popular it is over in Japanland, so yeah, she'll probably recognize a lot of the singing robots. But that probably won't be a problem, since the loids and UTAU are used to being recognized, ne? XD If she mentions anything about it being a program or something, it'll be behind a strikelock.